What sustained multi-disciplinary research can achieve: The space weather modeling framework

Halloween Storm Simulations with the Space Weather Modeling Framework

In late October and early November 2003 a series of some of the most powerful solar eruptions ever registered shook the heliosphere. These “Halloween storms” damaged 28 satellites, knocking two out of commission, diverted airplane routes and caused power failures in Sweden, among other problems. Long-distance radio communications were disrupted because of the effects on the ionosphere, and nort...

Validation of the space weather modeling framework using groundbased magnetometers

[1] Geomagnetically induced currents (GICs) can disrupt power grid operations, causing significant interference for many people; therefore, predictions of ground-based magnetic perturbations and their time derivatives are quite important. This study quantifies how well the University of Michigan’s Global MHD code predicts approximately 150 ground-based magnetometer traces for a number of storm-...

What we have accomplished and what we can achieve.

Using the framework method for the analysis of qualitative data in multi-disciplinary health research

BACKGROUND The Framework Method is becoming an increasingly popular approach to the management and analysis of qualitative data in health research. However, there is confusion about its potential application and limitations. DISCUSSION The article discusses when it is appropriate to adopt the Framework Method and explains the procedure for using it in multi-disciplinary health research teams,...

Can Viruses be Modified to Achieve Sustained Gene Transfer

It is very easy to replace a faulty gene in an immunocompromised mouse. First, one takes a well-characterized virus, such as an adenovirus or an adeno-associated virus, and incorporates the correct version of the faulty gene together with some regulatory sequences into the genome. Then, one transduces the recombinant genome into helper cells, which will add the viral capsid. At last, one inject...